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From Vibe Coding to Vibe Researching: OpenAI’s Mark Chen and Jakub Pachocki
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Software finally eats services - Aaron Levie
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America's Autism Crisis and How AI Can Fix Science with NIH Director Jay Bhattacharya
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Dylan Patel on the AI Chip Race - NVIDIA, Intel & the US Government vs. China
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Charlie Kirk and the Rise of Political Violence
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The Death of Search: How Shopping Will Work In The Age of AI
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How OpenAI Built Its Coding Agent
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Faster Science, Better Drugs
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Ben Horowitz: Why Hesitation is a CEO’s Worst Enemy
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Inside the $13T Mortgage Machine
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Chris Dixon on How to Build Networks, Movements, and AI-Native Products
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Mark Cuban on the NBA, Cost Plus Drugs, and How to Fix Politics
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The Little Tech Agenda for AI
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Building APIs for Developers and AI Agents
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How to Be Free: Shaka Senghor, Oprah Winfrey, Ben Horowitz
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Is Non-Consensus Investing Overrated?
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Jack Altman & Martin Casado on the Future of VC
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Chris Best of Substack on the Future of Media
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Katherine Boyle on Shawn Ryan
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Monopolies vs Oligopolies in AI
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The Top 100 Most Used AI Apps in 2025
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Aaron Levie and Steven Sinofsky on the AI-Worker Future
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Ben Horowitz on How a16z Was Built
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AI and Accelerationism with Marc Andreessen
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Can AI Fix Housing and Healthcare Affordability?
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Oren Cass & Noah Smith Debate the True Impact of Tariffs
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Dylan Patel: GPT-5, NVIDIA, Intel, Meta, Apple
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Google DeepMind Lead Researchers on Genie 3 & the Future of World-Building
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The State of American AI Policy: From ‘Pause AI’ to ‘Build’
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H20s to China + 15% with Chris Miller and Lennart Heim
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Grok, Genie 3, GPT-5 & the Rise of Vibe Coding
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Alex Danco on Speechwriting, Blogging, and Giving Founders Power
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Steven Sinofsky & Balaji Srinivasan on the Future of AI, Tech, & the Global World Order
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Marc Andreessen: Why Perfect Products Become Obsolete
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GPT-5 and Agents Breakdown – w/ OpenAI Researchers Isa Fulford & Christina Kim
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How to Build a Successful Company in an Era of Disruption
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Dwarkesh and Noah Smith on AGI and the Economy
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Balaji on How Tech Truly Wins Media
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AI Content and the War for Your Attention
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Balaji Srinivasan: How AI Will Change Politics, War, and Money
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Ben and Marc on New Media: Podcasts, Politics & the Collapse of Trust
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Critical Minerals: Mining for the Industrial Future
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The Future of Software Development - Vibe Coding, Prompt Engineering & AI Assistants
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Marc Andreessen and Joe Lonsdale on Tariffs and Trade
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America's Energy Problem: The Grid That Built America Can’t Power Its Future
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Aaron Levie on AI's Enterprise Adoption
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Ben Horowitz: What Founders Must Know About AI and Crypto
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Stablecoins & the Future Financial System
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How Andreessen Horowitz Disrupted VC & What’s Coming Next
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Enabling Agents and Battling Bots on an AI-Centric Web
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Marc Andreessen on Startup Timing
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Katherine Boyle: How Tech Can Rebuild America
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Where We Are in the AI Cycle
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Building Cluely: The Viral AI Startup that raised $15M in 10 Weeks
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Chris Dixon & Tyler Cowen on Crypto, AI, and Philosophy
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Why We Invested In Cluely
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The State of AI & Education
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How Apple Became So Reliant on China & What it Means For Their Future
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Adam Neumann: This is How You Build Iconic Companies
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What You Missed in AI This Week (Google, Apple, ChatGPT)
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Marc Andreessen & Jack Altman: Venture Capital, AI, & Media
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Chris Dixon: Stablecoins, Startups, and the Crypto Stack
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The State of Consumer Tech in the Age of AI
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Fei-Fei Li: World Models and the Multiverse
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Marc Andreessen: What We Got Right—and Wrong—About the Future of Tech
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Where Crypto Meets AI with Chris Dixon & David George
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Rick Rubin: Vibe Coding is the Punk Rock of Software
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Where Value Will Accrue in AI: Martin Casado & Sarah Wang
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Sovereign AI: Why Nations Are Building Their Own Models
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What Is an AI Agent?
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The Evolution of the Firm — with Ben and Marc
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Unbundling the BPO: How AI Is Disrupting Outsourced Work
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Marc Andreessen: Deep Vs. Broad Founders, AI in America, & the New Face of a16z
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What Super Agers Reveal About Preventing Disease
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Startups & Defense: Katherine Boyle on TBPN
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Do You Really Know Your ICP? Why It Matters and How to Find Out
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The Software Crisis Behind America's Infrastructure
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What Comes After Mobile? Meta’s Andrew Bosworth on AI and Consumer Tech
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The Dual-Use Founder: Vets Now Building For America
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The Future of Drone Warfare
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How to Build with the Department of Defense
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The Top 100 GenAI Products, Ranked and Explained
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Jensen Huang and Arthur Mensch on Winning the Global AI Race
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Why AI Voice Feels More Human Than Ever
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From Thesis to Meme to Fund: Building American Dynamism
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What Founders Get Wrong About Scaling – With Carta’s CEO
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Creativity vs Control: Where AI Fits in the Creative Toolbox
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Who Will Own the Internet? a16z’s Chris Dixon on AI and Crypto
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The Critical Technology in Finding Critical Materials
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DeepSeek: America’s Sputnik Moment for AI?
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Ben Horowitz Sharing History with Dr. Clarence Jones, MLK's Speechwriter
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How AI Is Changing Warfare with Brian Schimpf, CEO of Anduril
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RIP to RPA: How AI Makes Operations Work
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Marc Andreessen: Can Tech Finally Fix Healthcare?
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Building Substack: Reinventing Culture through Subscriptions
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Crypto Trends for 2025: Stablecoins, App Stores, UX, and More
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Super Staffing Healthcare, Codifying Compliance, & Scaling Services
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The Race for AI—Search, National Infrastructure, & On-Device AI
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Jobs of the Future, Harnessing Earth Observation, & Gaming Tech Advances
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Scaling Shopify: Tobias Lütke and Ben Horowitz on Building a Global Giant
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